| Ep | Date | Special Guest | Panel | Notes |
|---|---|---|---|---|
| 588 | January 4 | Jack E Leonard | Betsy, Bill, Bess, Henry | Musician Peanuts Taylor |
| 589 | January 11 | Bud Collyer and TTTT Panel | Betsy, Bill, Bess, Henry | Poston, Cass, Bean, Carlisle |
| 590 | January 18 | Alan King | Poston, Cass, Bean, Carlisle | Switch with To Tell The Truth panel |
| 591 | January 25 | Peter Lawford | Betsy, Bill, Bess, Henry | Author John Creasey, The Amazing Randi |
| 592 | February 1 | Kaye Ballard | Betsy, Bill, Bess, Henry | |
| 593 | February 8 | Shirl Conway | Betsy, Bill, Bess, Henry | |
| 594 | February 15 | No Guest | Betsy, Bill, Bess, Henry | Inventor Ray Kurzweil |
| 595 | February 22 | Buddy Hackett | Betsy, Bill, Bess, Henry | |
| 596 | March 1 | Olivia de Havilland & Bette Davis | Henry, Lorraine Bloy, Buddy Hackett, Betsy | Bloy is a stewardess who won a contest. |
| 597 | March 8 | Lucille Ball | Betsy, Garry Morton, Jayne Meadows, Henry | Morton is Lucille Ball's husband. |
| 598 | March 15 | Neil Sedaka | Betsy, Bill, Bess, Henry | |
| 599 | March 22 | Vivian Vance | Carol Channing, Bill, Bess, Henry | |
| 600 | March 29 | David Wayne | Betsy, Bill, Bess, Henry | Mike Henry |
| 601 | April 5 | Durward Kirby | Jayne Meadows, Bill, Bess, Henry | Writer David Wise |
| 602 | April 12 | Morey Amsterdam | Betsy, Bill, Bess, Henry | |
| 603 | April 19 | Woody Allen | Betsy, Bill, Bess, Henry | |
| 604 | April 26 | Edie Adams | Betsy, Bill, Bess, Henry | |
| 605 | May 3 | William Frawley | Betsy, Bill, Bess, Henry | Musician Keith Green |
| 606 | May 10 | Eydie Gorme | Betsy, Bill, Bess, Henry | |
| 607 | May 17 | George Hamilton | Betsy, Bill, Bess, Henry | Skateboard Demonstration |
| 608 | May 24 | Sam Levenson | Betsy, Bill, Bess, Henry | Warren Spahn |
| 609 | May 31 | Liza Minnelli | Betsy, Bill, Bess, Henry | |
| 610 | June 7 | Fritz Weaver | Betsy, Bill, Bess, Henry | |
| 611 | June 14 | Don DeFore | Betsy, Bill, Bess, Henry | Football's Frank Ryan |
| 612 | June 21 | Arlene Francis | Betsy, Bill, Bess, Henry | |
| 613 | June 28 | Jayne Meadows | Betsy, Bill, Bess, Henry | |
| 614 | July 5 | Tony Randall | Betsy, Bill, Bess, Henry | |
| X | July 12 | RERUN | ||
| X | July 19 | RERUN | ||
| X | July 26 | RERUN | ||
| X | August 2 | RERUN | ||
| X | August 9 | RERUN | ||
| X | August 16 | RERUN | ||
| X | August 23 | RERUN | ||
| X | August 30 | RERUN | ||
| X | September 6 | RERUN | ||
| 615 | September 13 | Carol Burnett | Betsy, Bill, Bess, Henry | Wrestler Happy Humphrey |
| 616 | September 20 | Soupy Sales | Betsy, Bill, Bess, Henry | |
| 617 | September 27 | Fred Gwynne | Jayne Meadows, Bill, Bess, Henry | |
| 618 | October 4 | Arthur Godfrey | Carol Channing, Bill, Bess, Henry | |
| 619 | October 11 | Peter Falk | Betsy, Bill, Bess, Henry | Sculptor/Musician Francois Baschet |
| 620 | October 18 | Buddy Hackett | Betsy, Bill, Bess, Henry | |
| 621 | October 25 | Alan King | Betsy, Bill, Bess, Buddy Hackett | Henry Morgan hosts |
| 622 | November 1 | Durward Kirby | Betsy, Bill, Bess, Henry | |
| 623 | November 8 | Vivian Vance | Betsy, Bill, Bess, Henry | |
| 624 | November 15 | Omar Sharif | Betsy, Bill, Bess, Henry | Guinness authors Norris and Ross McWhirter |
| 625 | November 22 | Ethel Merman | Betsy, Bill, Bess, Henry | Satchel Paige |
| X | November 29 | NO SHOW | Leonard Bernstein Young People's Concert | |
| 626 | December 6 | George Maharis | Betsy, Bill, Bess, Henry | Aviator Bernt Balchen |
| 627 | December 13 | Debbie Bryant | Betsy, Bill, Bess, Henry | Bryant is Miss America 1966 |
| 628 | December 20 | Christmas Show | Betsy, Bill, Bess, Henry | Musician Carole Reinhart |
| 629 | December 27 | Louis Armstrong | Betsy, Bill, Bess, Henry | Pool player Billy Staton |
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